Two opposite corners of a cube make a body diagonal. There will be four body diagonals connecting the opposite corners to which there will correspond the following vectors (the negative of these vectors will work also).
\begin{align*}
\amp \vec d_1 = \left[ (0,0,0) \rightarrow (1,1,1)\right] = \hat u_x + \hat u_y + \hat u_z\\
\amp \vec d_2 = \left[ (1,0,0) \rightarrow (0,1,1)\right] = - \hat u_x + \hat u_y + \hat u_z\\
\amp \vec d_3 = \left[ (0,1,0) \rightarrow (1,0,1)\right] = \hat u_x - \hat u_y + \hat u_z\\
\amp \vec d_4 = \left[ (0,0,1) \rightarrow (1,1,0)\right] = \hat u_x + \hat u_y - \hat u_z
\end{align*}
I will work out the angle between \(\vec d_1\) and \(\vec d_2\) and you can practice with the others.
\begin{equation*}
\cos\theta = \frac{\vec d_1 \cdot \vec d_2}{|\vec d_1|\ |\vec d_2|} =\frac{1}{\sqrt{3}\ \sqrt{3}} = \frac{1}{3}.
\end{equation*}
Therefore, the angle between the two vectors is \(\cos^{-1}(1/3)\text{.}\)